A single touch, a single chip and you can be healed of anything.
This is the implication of a breakthrough device developed by Researchers at The Ohio State University Wexner Medical Center and Ohio State’s College of Engineering.
The device heals organs with a single touch by delivering new DNA or RNA into living skin cells to change their function.
The breakthrough in regenerative medicine has been published in the journal Nature Nanotechnology and explains a new technology called Tissue Nanotransfection (TNT).
Here is the key point: the technology can generate any cell type in a patient’s own body.
The implications are enormous, as explained in the video below.
“By using our novel nanochip technology, injured or compromised organs can be replaced. We have shown that skin is a fertile land where we can grow the elements of any organ that is declining,” said Dr. Chandan Sen, director of Ohio State’s Center for Regenerative Medicine & Cell Based Therapies, who co-led the study with L. James Lee, professor of chemical and biomolecular engineering with Ohio State’s College of Engineering in collaboration with Ohio State’s Nanoscale Science and Engineering Center.
In their study the researchers were able to reprogram skin cells of pigs and mice to become vascular cells in badly injure legs that had no blood flow. Within one week the blood flow returned and after two weeks the leg healed completely and was saved.
Dr. Sen says the technology isn’t only applicable to skin cells. It can be used on other tissues within the body. In lab tests skin cells were also reprogramed to become nerve cells which were injected into the brains of mice that had suffered stroke.
The scientist says the technology has been successful 98 percent of the time.
It seems impossible.
Just one touch, a process that takes less than a second and is non-invasive. And off you go, all better soon.
The procedure involves one touch of the skin with the device and the “biological cargo” is delivered by zapping the device with a small electrical charge that’s barely felt by the patient. The chip isn’t implanted and the reprogramming starts immediately.
The press release explains that TNT technology has two major components: First is a nanotechnology-based chip designed to deliver cargo to adult cells in the live body. Second is the design of specific biological cargo for cell conversion. This cargo, when delivered using the chip, converts an adult cell from one type to another.
That’s not all.
The technology keeps the cells in the body under immune surveillance, so immune suppression is not necessary. Think what this can mean for organ regeneration and, restoring of any aging tissue, including blood vessels and nerve cells.
Sen said they plan to start clinical trials next year to test this technology in humans.