Exciting: Compound in Plants Found to Halt Growth of Melanoma Cancer Cells

Exciting: Compound in Plants Found to Halt Growth of Melanoma Cancer Cells

Exciting: Compound in Plants Found to Halt Growth of Melanoma Cancer Cellsby Mike Barrett

Showcasing once again how numerous food-based substances are able to both treat and protect against cancer, scientists from the Texas Biomedical Research Institute have found for the first time that a natural, plant-derived substance known as gossypin is capable of treating the deadliest form of skin cancer – melanoma.

In the study, published in the journal Molecular Cancer Therapeutics, researchers found gossypin was able to inhibit human melanoma cell proliferation in melanoma cell lines where two genetic mutations occur. In the lab tests using cell cultures, gossypin was also shown to inhibit the growth of human melanoma cells and reduce tumor volume while increasing survival rate.

“We identified gossypin as a novel agent with dual inhibitory activity towards two common mutations that are the ideal targets for melanoma treatment,” said Texas Biomed’s Hareesh Nair, Ph.D. ”Our results indicate that gossypin may have great therapeutic potential as a dual inhibitor of mutations called BRAFV600E kinase and CDK4, which occur in the vast majority of melanoma patients. They open a new avenue for the generation of a novel class of compounds for the treatment of melanoma.”

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The American Cancer Society estimates that 76,690 individuals will be diagnosed with melanoma in 2013. Additionally, an estimated 9,480 people are expected to die of melanoma this year. The research out of Texas Biomedical Research Institute once again shows how natural substances can offer promise — even for those suffering from the deadliest type of skin cancer.

Other Natural Compounds Recognized for Inhibiting Cancer

As we all know, the above piece of research is far from the first and the last to reveal the healing capabilities of natural compounds in food. In other recent research, compounds in apples known as oligosaccharides were found to kill up to 46% of human colon cancer cells and even outperform common chemo drugs. Excitingly, the the compounds can be derived from the waste of an apple (known as pomace) after it has been juiced. That’s a lot of  pomace from the apple juice industry.

In another example, a study examining the beneficial properties of milk thistle stated: “there is strong preclinical evidence for silymarin’s (milk thistle’s) hepatoprotective and anticarcinogenic effects, including inhibition of cancer cell growth in human prostate, skin, breast, and cervical cells.” What’s more, milk thistle was also found to protect against chemotherapy’s toxic effects.

There is no shortage of natural solutions for cancer or most other ailments; it’s all about doing your own research and discovering these natural healers for yourself.

Additional Sources:

Medical News Today

via Natural Society

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Aloe Vera May Prevent, Stop Progression of Skin Cancer

Aloe Vera May Prevent, Stop Progression of Skin Cancer

aloby Elizabeth Renter,
The benefits of aloe vera for your skin are undeniable. If you’ve ever cut open a leaf for use on a cut, scrape, or sunburn, you’ve experienced it first hand. But aloe vera may possess even greater healing power than many realize, potentially preventing and halting skin cancer in its tracks.

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In addition to reducing wrinkles, researchers from the University of Belgrade School of Medicine recently confirmed that the constituents in aloe vera stops proliferation of cells that accompanies skin cancer. With skin cancer, cells proliferate (or multiple rapidly) as skin tumors develop. To stop this cell growth, you can stop the tumors from developing.

The researchers found that Aloe-emodin stopped cell proliferation. In conjunction with this finding, the researchers discovered that although the isolated aloe compounds were protective, the whole herb extracts were even better.

What this means is that identifying the beneficial compound in the plant is great, but when you remove it from the plant to isolate it and use the isolated compound in a treatment, it is far less effective than when used as part of the plant.

Additionally, aloe vera contains many other compounds adding to it’s antioxidant properties and healing abilities. Case Adams, Naturopath from GreenMedInfo reports:

The gel of the Aloe leaf and its other plant parts contain many constituents outside of those tested in these studies, including quercetin, luteolin, apigenin, kaempferol, isoorientin, isovitexin, saponarin, lutonarin, chlorogenic acid, pectic acid, caffeic acid, 5-P-coumaroylquinic acid, caffeoylshikimic acid, feruloylquinic acid, coumaric acid, ferulic acid, as well as glycosylchromone aloeresin B, and aloin, which is a precursor to Aloe-emodin.

Other studies have also demonstrated aloe’s ability to stop the progression of skin cancer when applied directly to the skin. It is suspected that aloe very stimulates the production of melanin and other protective substances. So, using fresh aloe vera gel for sunburn relief may pull double-duty, soothing the burn and protecting the skin from cancer. And of course everyone knows that burn relief is among many other health benefits of aloe vera.

One of the best things about aloe vera is you can grow it yourself in your home or your yard (if you are in a warmer climate). It’s a great first aid treatment and is excellent for a variety of skin conditions.

Additional Sources:

Webmd
Read more: Natural Society 
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